Marwa Hassan Mohamed Ahmed
- 01062309003
- 01012926014
- 01012926014
- [email protected]
- [email protected]
- Nationality: Egyptian
- Governorate: Giza
- Address: 6th October city
- Gender: Female
Biography
I, Marwa Hassan, am an Assistant Professor at Immunology Department, Theodor Bilharz Research Institute (TBRI), Giza, Egypt. I graduated from Faculty of Medicine, Kasr El-Aini, Cairo University, in 2006. I earned Master's and MD Degrees in Clinical and Chemical Pathology from the Faculty of Medicine, Kasr El-Aini, Cairo University, Egypt, in 2012 and 2015, respectively. My areas of expertise include molecular biology, epigenetics, stem cell research, and monoclonal antibody production. I have served as a Principal Investigator, Co-Principal Investigator, and participant in 12 research projects financed by TBRI, and I have also acted as a Co-Principal Investigator and participant in 7 research projects sponsored by international and national agencies. I have over 30 articles in peer-reviewed international journals and act as a reviewer for more than 40 esteemed international journals.
Research Fields
Molecular Biology, Stem cells, Monoclonal Ab production, and liver diseases
- Division : Immunology and Therapeutic Evaluation Division
- Department : Immunology Department
- Specialization : Medicine
- Degree : Assistant Professor
- Job Title : Assistant Professor
- Work Status : Active / In Service
- Google Scholar : Click here
- Scopus : Click here
Published Research Papers (10)
Azithromycin Mitigates Experimental Cryptosporidiosis-Driven Ileocecal Adenocarcinoma by Modulating Autophagy, Apoptosis, and PI3K/AKT Signaling
ScopusResearch Type: Research article | Domain: Tropical and Parasitic Diseases
Publish Type: Published
Publish Date: 2026-05-29
Background/Objectives: Cryptosporidium parvum (C. parvum), a waterborne intestinal parasite, causes severe, persistent infections in immunocompromised hosts and has been linked to the onset of ileocecal adenocarcinoma. However, the molecular pathways linking chronic infection to carcinogenesis remai...
Novel lncRNA Signature (UFC1/PTENP1) as a Molecular Biomarker for the Diagnosis and Prognosis of Hepatocellular Carcinoma in an Egyptian Cohort
ScopusResearch Type: Research article | Domain: Genetics and Molecular Biology
Publish Type: Published
Publish Date: 2026-03-29
Long non-coding RNAs (lncRNAs) are key regulators of gene expression and play critical roles in cancer-related signaling networks. Dysregulation of antagonistic lncRNAs may contribute to hepatocarcinogenesis and disease progression. This study investigated the clinical significance and predictive va...
Integrating CTLA-4 genetics and soluble isoforms for the stratification of HCV-related hepatocellular carcinoma risk and aggressiveness
ScopusResearch Type: Research article | Domain: Genetics and Molecular Biology
Publish Type: Published
Publish Date: 2025-11-15
Host genetic factors influencing immune regulation are believed to modulate susceptibilityto hepatitis C virus (HCV) and related hepatocellular carcinoma (HCC). This study aimedto investigate the association of Cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4)genetic variants with HCV-related HCC...
Genetic variants and soluble isoforms of PD-1/PD-L1 as novel biomarkers for pancreatic ductal adenocarcinoma (PDAC) susceptibility and prognosis
ScopusResearch Type: Research article | Domain: Genetics and Molecular Biology
Publish Type: Published
Publish Date: 2025-09-12
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive neoplasmoften diagnosed at advanced stages. Immune checkpoint molecules, particularly programmedcell death protein-1 (PD-1) and its ligand PD-L1, are pivotal in tumor immuneevasion. Genetic polymorphisms in PD-1/PD-L1 and the...
Innovative therapeutic modalities of purified platelet-derived growth factors on PDX1, Neurog3, and renin expressions in STZ-induced diabetic nephropathy and pancreatic injury
ScopusResearch Type: Research article | Domain: Gastroenterology and Digestive System Diseases
Publish Type: Published
Publish Date: 2025-08-18
Diabetic nephropathy is the predominant etiology of advanced renal disease, and its prevalence has increased significantly over recent years. The primary management strategy focuses on controlling identified risk factors; however, this approach only slows disease progression and cannot halt or rever...
Impact of semaglutide on health outcomes and mood in obese heart failure patients: a retrospective analysis
ScopusResearch Type: Research article | Domain: Pharmacology
Publish Type: Published
Publish Date: 2025-06-02
Background and Objective: Obesity is common in heart failure (HF), worsening quality of life and depressive symptoms. While semaglutide, a GLP-1 agonist, aids weight loss in obese adults, its impact on health and mood in obese HF patients is unclear. This study evaluated semaglutide’s effects on bod...
Exploiting regulatory T cells (Tregs): Cutting-edge therapy for autoimmune diseases
ScopusResearch Type: Review article | Domain: Immunology
Publish Type: Published
Publish Date: 2025-04-10
Regulatory T cells (Tregs) are a specialized subset of suppressive T cells that are essential for maintaining self-tolerance, regulating effector T cells, managing microbial infections, preventing tumors, allergies, and autoimmune disorders, and facilitating allograft transplantation. Disruptions in...
Protective effects of cilostazol via the HNF1α/FXR signalling pathway and anti-apoptotic mechanisms in a rat model of estrogen-induced intrahepatic cholestasis
ScopusResearch Type: Research article | Domain: Hepatology and Liver Diseases
Publish Type: Published
Publish Date: 2024-10-01
Currently, there is a lack of targeted medications for estrogen-induced intrahepatic cholestasis (EIC), and the primary objective in managing this condition is to safeguard liver function. Consequently, this study was conducted to examine the pharmacological efficacy of cilostazol (CTZ) in the manag...
Telocytes and ezrin expression in normal-appearing tissues adjacent to urothelial bladder carcinoma as predictors of invasiveness and recurrence
ScopusResearch Type: Research article | Domain: Nephrology
Publish Type: Published
Publish Date: 2023-04-15
Recurrence and progression rates vary widely among diferent histological subtypes of bladdercancer (BC). Normal‑appearing mucosa in non‑muscle invasive bladder cancer and muscle‑invasivebladder cancer in cystoscopy and histopathology is a factor in staging and treatment. Telocytes(TCs) are spindle‑s...
Co-treatment with Esculin and erythropoietin protects against renal ischemia-reperfusion injury via P2X7 receptor inhibition and PI3K/Akt activation
ScopusResearch Type: Research article | Domain: Nephrology
Publish Type: Published
Publish Date: 2022-04-14
Renal ischemia/reperfusion (RI/R) is a critical clinical outcome with slightly reported improvement inmortality and morbidity. Efective therapies are still crucially required. Accordingly, the therapeuticefects of esculin (ESC, LCESI‑MS/MS‑isolated compound from Vachellia farnesiana lowers extract,w...
MD - Clinical and Chemical Pathology - Faculty of Medicine, Cairo University
January 2013 to November 2015
Assistant Professor - Theodor Bilharz Research Institute
1 July 2021 - Current
Assistant Professor at Immunology Department, Theodor Bilharz Research Institute
Molecular Diagnosis
Molecular diagnosis of GIT and liver diseases.